BDBM379760 US9926281, Compound 220::US9926281, Compound 425

SMILES CC1(CC(CO)C(=O)N2CCN(CC2)c2cc(Cl)cc(Cl)c2)NC(=O)NC1=O

InChI Key InChIKey=LHKXLEZLEFHFJV-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 379760   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM379760(US9926281, Compound 220 | US9926281, Compound 425)
Affinity DataIC50:  3.84E+3nMAssay Description:MMP-14:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP14 (Biomol, Cat #SE-259...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM379760(US9926281, Compound 220 | US9926281, Compound 425)
Affinity DataIC50:  2.82E+3nMAssay Description:MMP-14:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP14 (Biomol, Cat #SE-259...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent